Increased seminal reactive oxygen species levels in patients with varicoceles correlate with varicocele grade but not with testis size.
نویسندگان
چکیده
Increased levels of reactive oxygen species (ROS) are associated with clinical varicoceles; however, its correlation with varicocele grade and testis size is unknown. In our study, seminal ROS levels showed significant correlation with left varicocele grade and significantly elevated seminal ROS levels were seen in men with left varicocele grade 2 and 3 compared to grade 1.
منابع مشابه
Impact of clinical varicocele and testis size on seminal reactive oxygen species levels in a fertile population: a prospective controlled study.
OBJECTIVE To investigate: 1) the impact of clinical varicocele on reactive oxygen species (ROS) levels in neat and washed semen in a proven fertile population; and 2) the correlation between ROS levels, testicular volume, and varicocele grade in the same population of fertile men. DESIGN Prospective controlled clinical study. SETTING Andrology laboratory at tertiary-care hospital. PATIENT...
متن کاملEvaluation of nuclear DNA damage in spermatozoa from infertile men with varicocele.
OBJECTIVE To examine levels of sperm DNA damage and oxidative stress (OS) in infertile men with varicocele. DESIGN Prospective controlled study. SETTING Male infertility clinic, Glickman Urological Institute, Cleveland Clinic Foundation, Cleveland, Ohio. PATIENT(S) Thirty-one infertility patients and 16 fertile controls. INTERVENTION(S) Sperm DNA fragmentation index (DFI), levels of sem...
متن کاملMolecular and other predictors for infertility in patients with varicoceles.
Varicoceles are a treatable cause of male infertility, but very clinically diverse. Both histologic and molecular changes occur in the testes of men with varicocele. Physical measurements (scrotal temperature, testicular volume, pressure within the pampiniform plexus, basal lamina thickness) correlate with prognosis, but these correlations have not been accepted as predictors of successful repa...
متن کاملReactive oxygen species (ROS) production in seminal fluid correlate with the severity of varicocele in infertile men
Background: Reactive oxygen species (ROS) are a group of free radicals that in excessive amounts have negative influence on sperm quality and function. Objective: To study the effect of varicocele and its severity on the level of ROS in infertile men with clinical varicocele. Materials and Methods: In this controlled prospective study, 42 men with clinically diagnosed left varicocele and 30 fer...
متن کاملP-27: The Effect of Varicocelectomy onThe Serum Testosterone Level in Infertile Men with Grade (II - III) Varicocele
Background: To determine whether men with varicoceles have lower testosterone levels than those without and to ascertain if testosterone levels increase after varicocelectomy and or to determine whether the varicocele grade is related to the degree of improvement in serum testosterone levels after varicocelectomy and also older age is associated with improvements in testosterone after varicocel...
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ورودعنوان ژورنال:
- Fertility and sterility
دوره 82 6 شماره
صفحات -
تاریخ انتشار 2004